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Clinical trials that are designed to help inform practice in the real world are referred to as pragmatic trials. They are typically described as focusing on practical aspects of study design that include the recruitment and consent process, as well as adherence and the use of standard equipment.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which utilized a variety of investigators and participants from various geographical areas. This type of heterogeneity is required for practical trials to be valid and also helps to reduce bias in the results. A high degree of heterogeneity, 무료 프라그마틱 however could cause issues with the design of the trial.

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The purpose of pragmatic trials is to mimic real-life scenarios and to achieve maximum validity externally. Usually, they are commissioned by policymakers and practitioners in order to guide their decisions. They can also be a great way to identify the cause-effect relationship between an intervention and its results. They should, however, not, be used to replace explanation studies.

The pragmatism idea is controversial and there are doubts about whether pragmatic trials should be used to replace explanation tests or if they should serve as an alternative to them. Schwartz and Lellouch1 suggested a distinction between explanatory studies, which support the physiological hypothesis or clinical hypothesis, and pragmatic trials that aid in the decision-making process for policy and practice. They also suggested a framework dubbed PRECIS for pragmatic trials.2 The tool was designed to define the characteristics of a practical study, including the recruitment, design, and delivery of the intervention and follow-up.

There is a growing trend in the number of pragmatic trials published. A recent Medline search using the keywords naturalistic and pragmatic, which was limited to controlled trials that are randomized (RCTs), yielded 34 articles, 프라그마틱 슬롯 무료체험 which are shown in red in Figure 2. This indicates that the health sciences community is becoming more acquaint to the subject of pragmatism. It is important to keep in mind, however, that the majority of these studies were conducted in primary care settings.